High-resolution fluorescence imaging is essential in nanoscience andbiological sciences. Due to the diffraction limit, conventional imagingsystems can only resolve structures larger than 200 nm. Here, weintroduce a new fluorescence imaging method that enhances the resolutionby using a high-index scattering medium as an imaging lens.Simultaneously, we achieve a wide field of view. We develop a new imagereconstruction algorithm that converges even for complex objectstructures. We collect two-dimensional fluorescence images of acollection of 100 nm diameter dye-doped nanospheres, and demonstrate adeconvolved Abbe resolution of 116 nm with a field of view of 10 μm 10μm. Our method is robust against optical aberrations and stage drifts,and therefore is well suited to image nanostructures with highresolution under ambient conditions.

http://dx.doi.org/10.1364/OPTICA.2.000424

H. Y?lmaz, E.G. van Putten, J. Bertolotti, A. Lagendijk, W.L. Vos, A. P. Mosk

2015

04/2015

Optica

2

424-429

microscopy, scattering media